| 发明名称 |
DIMETHYL-BENZOIC ACID COMPOUNDS |
| 摘要 |
<p>The present invention provides a compound of the Formula II: wherein A is: * R 1 is CH3, CF 3, or F; * R 2 is H, CH3, or F; * R 3 is CH3, OCH 3, OH, F; R 4 is OH or CH 20H; and * X is CH or N; These compounds are selective EP4 inhibitors and are useful for the treatment of inflammatory conditions such as arthritis.</p> |
| 申请公布号 |
PH12015500008(A1) |
申请公布日期 |
2015.03.02 |
| 申请号 |
PH2008120155000 |
申请日期 |
2015.01.05 |
| 申请人 |
ELI LILLY AND COMPANY |
发明人 |
BLANCO-PILLADO, MARIA-JESUS;VETMAN, TATIANA NATALI;FISHER, MATTHEW JOSEPH;KUKLISH, STEVEN LEE |
| 分类号 |
A61K31/402;A61K31/4025;A61K31/445;A61K31/4709;A61P29/00;C07D207/08;C07D211/42;C07D211/46;C07D401/04 |
主分类号 |
A61K31/402 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
