| 发明名称 |
SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS |
| 摘要 |
Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. |
| 申请公布号 |
US2015057291(A1) |
申请公布日期 |
2015.02.26 |
| 申请号 |
US201414534629 |
申请日期 |
2014.11.06 |
| 申请人 |
NERVIANO MEDICAL SCIENCES S.R.L. |
发明人 |
Lombardi Borgia Andrea;Menichincheri Maria;Orsini Paolo;Panzeri Achille;Perrone Ettore;Vanotti Ermes;Nesi Marcella;Marchionni Chiara |
| 分类号 |
C07D405/12 |
主分类号 |
C07D405/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising a therapeutically effective amount of N-[5-(3,5-difluorobenzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide, or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable excipient, carrier or diluent. |
| 地址 |
Nerviano (MI) IT |
