发明名称 |
Enantiomeric compounds, use thereof for the treatment or prevention of viral diseases, autoimmune diseases or organ or tissue transplantation rejection and methods of making same |
摘要 |
<p>The present invention provides methods for treating Acquired Immunodeficiency Syndrome (AIDS) and other viral diseases and Human Immunodeficiency Virus (HIV) related infections by administering one or more compounds of formula I: wherein: the dotted line represents a single or a double bond; and R1 and R2 are the same or different and independently of each other represent—CH2OH,—CH2OR4,—CH(OH)CH3,—CH(OR4)CH3 or a group represented by the formula: or salts or hydrates thereof in a carrier which minimizes micellar formation or van der Waals attraction of molecules of said compound. The invention also provides S enantiomeric forms of such compounds which possess the ability to inhibit cell growth whilst being of low toxicity to such cells and methods of making such compounds.</p> |
申请公布号 |
IL178094(A) |
申请公布日期 |
2015.02.26 |
申请号 |
IL20060178094 |
申请日期 |
2006.09.14 |
申请人 |
SHMUEL BITTNER;NEW ERA BIOTECH LTD.;ELIAHU KAPLAN;ELIAKIM HARLEV |
发明人 |
SHMUEL BITTNER;ELIAHU KAPLAN;ELIAKIM HARLEV |
分类号 |
A61K31/165;A61K31/4045;A61K31/405;C07C233/11;C07C233/22;C07C235/34;C07D209/14;C07D209/16;C07D209/18;C07D233/54;C08G65/333 |
主分类号 |
A61K31/165 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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