| 发明名称 |
ALKYNYL ALCOHOLS AND METHODS OF USE |
| 摘要 |
The invention relates to compounds of Formula (0): wherein Q, A1-A8, R4 and R5 and each has the meaning as described herein. Compounds of Formula (0) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over- activation of NF-kB signaling is observed. |
| 申请公布号 |
CA2921880(A1) |
申请公布日期 |
2015.02.26 |
| 申请号 |
CA20142921880 |
申请日期 |
2014.08.22 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BLAQUIERE, NICOLE;BURCH, JASON;CASTANEDO, GEORGETTE;FENG, JIANWEN A.;HU, BAIHUA;STABEN, STEVEN;WU, GUOSHENG;YUEN, PO-WAI |
| 分类号 |
C07D401/14;A61K31/4155;A61K31/416;C07D401/10;C07D403/10;C07D403/14;C07D413/10;C07D413/14;C07D417/10;C07D471/04;C07D487/04;C07D491/048;C07D491/052;C07D495/04;C07D513/04 |
主分类号 |
C07D401/14 |
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