| 发明名称 |
IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS |
| 摘要 |
<p>The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.</p> |
| 申请公布号 |
CA2663537(C) |
申请公布日期 |
2015.02.24 |
| 申请号 |
CA20072663537 |
申请日期 |
2007.10.01 |
| 申请人 |
AMGEN INC. |
发明人 |
TOCKER, JOEL;PESCHON, JACQUES J.;FITZPATRICK, DAVID;SMOTHERS, JAMES F.;MEHLIN, CHRISTOPHER;LIM, AI CHING |
| 分类号 |
C07K16/28;A61K39/395;A61P37/02 |
主分类号 |
C07K16/28 |
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