Enhanced animal cell growth using ultrasound

摘要

A method of increasing animal cell growth and monoclonal antibody production in an animal cell or cell culture includes the use of ultrasound at a frequency greater than about 1 MHz.

主权项

1. A method of increasing the rate of growth of an animal cell culture, comprising exposing the animal cell culture to ultrasound having a frequency from greater than about 1 MHz to 2 MHz,
wherein the ultrasound is pulsed, and the animal cell culture is a hybridoma cell culture or a CHO cell culture.