摘要 |
The present invention pertains generally to the field of therapy and medical treatment, and more specifically to certain compounds of the following formula (for convenience, collectively referred to herein as "short-chain phosphatidylcholine lipids" and "SCPC lipids"), which, inter alia, are useful in methods of improving drug delivery, bioavailability, and efficacy. The present invention also pertains to pharmaceutical formulations, and more specifically to co-formulations of known drugs (e.g., amphiphilic drugs) (e.g., anthracyclines) (e.g., doxorubicin) with these SCPC lipids, and their use, for example, in therapy. |
申请人 |
STICHTING HET NEDERLANDS KANKER INSTITUUT - ANTONI VAN LEEUWENHOEK ZIEKENHUIS;ERASMUS UNIVERSITY MEDICAL CENTRE;RIJKSUNIVERSITEIT GRONINGEN |
发明人 |
VAN HELL, ALBERT;VERHEIJ, MARCEL;MARRINK, SIEWERT, JAN;KONING, GERBEN |