| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a nucleic acid probe which is not necessary to be adjusted every target nucleic acid because the nucleic acid probe is added with an expensive fluorescent mark. <P>SOLUTION: This nucleic acid probe set is formed of: a fluorescent probe (A) composed of oligonucleotide containing nucleotide (a) marked with a fluorescent substance; and a binding probe (B) composed of oligonucleotide having a fluorescent binding region (b1) hybridized by the fluorescent probe (A), and a target nucleic acid binding region (b2) hybridized with a target nucleic acid (C). The nucleic acid probe set is designed so that, when the fluorescent probe (A) is hybridized with the fluorescent binding region (b1) and the target nucleic acid (C) is hybridized with the target nucleic binding region (b2), guanine in the target nucleic acid (C) is mutually reacts with the fluorescent substance (d) marked at the nucleotide (a), and a fluorescent character of the fluorescent substance (d) is changed. <P>COPYRIGHT: (C)2013,JPO&INPIT</p> |
