| 摘要 |
At least one amino acid selected from the group consisting of L-arginine, L-citrulline and L-ornithine can be produced with high efficiency by culturing a coryneform bacterium in a culture medium to produce and accumulate the amino acid in a culture and then collecting the amino acid from the culture, wherein the coryneform bacterium is produced by introducing a deletion, substitution or addition of at least one nucleotide into at least one gene which is present in chromosomal DNA of a parent strain and encodes a protein having an L-arginine, L-citrulline or L-ornithine uptake activity so that the activity of uptake of the amino acid in the coryneform bacterium is reduced or lost compared with that in the parent strain, and can produce the amino acid. |
