Method for manufacturing of DNA hydrogel with adhesive characteristics

摘要

The present invention relates to a method for manufacturing a DNA hydrogel which has adhesive characteristics using a compound which includes two or more pyrogallol functional groups as a cross-linking agent. The present invention can be used for medicine for a gene treatment and an adhesive carrier for a local injection since the present invention is able to: synthesize the DNA hydrogel in a short time by combining a compound which includes two or more pyrogallol functional groups and a DNA solution of high concentration; control the physical properties of the DNA hydrogel according to the concentration of the compound which includes two or more pyrogallol functional groups; and emit DNA according to the decomposition degree of the compound which includes two or more pyrogallol functional groups which are a cross-linking agent when being exposed to a solution of pH7.4.