ORALLY ADMINISTRABLE GALLIUM COMPOSITIONS AND METHODS OF USE

摘要

Provided are pharmaceutical gallium compositions that are particularly useful for oral administration. The pharmaceutical compositions include solid, liquid, and paste formulations, which have high oral gallium bioavailability and are suitable for human and veterinary applications. The compositions comprise pharmaceutically acceptable gallium compounds, such as gallium maltolate, gallium 8-quinolinolonate, or gallium nitrate, together with certain viscosity-increasing agents, such as water-soluble forms of methylcellulose or carboxymethylcellulose.

主权项

1. A method for increasing the oral bioavailability of gallium comprising the administration of a pharmaceutical composition comprising gallium 8-quinolinolate and a pharmaceutically acceptable viscosity-increasing agent.