| 摘要 |
The present invention is directed to piperazine derivatives, pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. |
| 申请人 |
MERCK SHARP & DOHME CORP.;MSD R&D (CHINA) CO., LTD;WILLIAMS, PETER D.;MCCAULEY, JOHN A.;BENNETT, DAVID JONATHAN;BUNGARD, CHRISTOPHER J.;CHANG, LEHUA;CHU, XIN-JIE;DWYER, MICHAEL P.;HOLLOWAY, M. KATHARINE;KEERTIKAR, KARTIK M.;LOUGHRAN, H. MARIE;MANIKOWSKI, JESSE J.;MORRIELLO, GREGORI J.;SHEN, DONG-MING;SHERER, EDWARD C.;SCHULZ, JURGEN;WADDELL, SHERMAN TIM;WISCOUNT, CATHERINE M.;ZORN, NICOLAS;TUMMANAPALLI, SATYANARAYANA;SIVALENKA, VIJAYASARADHI;HU, BIN;JI, TAO;ZHONG, BIN |
发明人 |
WILLIAMS, PETER D.;MCCAULEY, JOHN A.;BENNETT, DAVID JONATHAN;BUNGARD, CHRISTOPHER J.;CHANG, LEHUA;CHU, XIN-JIE;DWYER, MICHAEL P.;HOLLOWAY, M. KATHARINE;KEERTIKAR, KARTIK M.;LOUGHRAN, H. MARIE;MANIKOWSKI, JESSE J.;MORRIELLO, GREGORI J.;SHEN, DONG-MING;SHERER, EDWARD C.;SCHULZ, JURGEN;WADDELL, SHERMAN TIM;WISCOUNT, CATHERINE M.;ZORN, NICOLAS;TUMMANAPALLI, SATYANARAYANA;SIVALENKA, VIJAYASARADHI;HU, BIN;JI, TAO;ZHONG, BIN |
