<p>Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.</p>
申请公布号
CA2780547(C)
申请公布日期
2015.02.03
申请号
CA20102780547
申请日期
2010.11.10
申请人
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
发明人
WANG, SHAOMENG;YU, SHANGHAI;SUN, WEI;KUMAR, SANJEEV;SUN, DUXIN;ZOU, PENG;ZHAO, YUJUN;MCEACHERN, DONNA
