Phenoxymethyl heterocyclic compounds

摘要

Phenoxymethyl compounds that inhibit at least one phosphodiesterase 10 are described as are pharmaceutical compositions containing such compounds an methods for treating various CNS disorders by administering such compounds to a patient in need thereof.

主权项

1. A method for treating a central nervous system (CNS) disorder selected from the group consisting of Huntington's disease, schizophrenia, a schizo-affective condition, obsessive compulsive disorder and psychosis associated with Parkinson's disease, the method comprising administering to a human in need thereof a therapeutically effective amount of 4-(4-(imidazo[1,2-b]pyridazin-2-ylmethoxy)phenyl)-2,2-dimethyl-5-(pyridin-4-yl)furan-3(2H)-one or a pharmaceutically acceptable salt thereof.