摘要 |
Indolealkylamines of the formula <IMAGE> wherein Ind is 1-R4-2-R5-indol-3-yl or the corresponding group in which the benzene ring is monosubstituted to trisubstituted by alkyl, O-alkyl, S-alkyl, OH, F, Cl, Br, CF3 or CN; A is -(CH2)4-, -(CH2)3-CO- or -CO-(CH2)2-CO-; R1 is H or methyl; R2 is H or together with R3 is a C-C bond; R3 is H or together with R2 is a C-C bond; R4 and R5 are each H, alkyl, or phenyl; and Ar is phenyl or phenyl monosubstituted or disubstituted by alkyl, F, Cl, Br, I or CF3; wherein alkyl in each case is of 1-4 carbon atoms; and the physiologically acceptable acid addition salts thereof possess valuable pharmacological properties.
|
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
HAUSBERG, HANS-HEINRICH;KOPPE, VOLKER;POETSCH, EIKE;SAIKO, OTTO;SEYFRIED, CHRISTOPH |