发明名称 Indolealkylamines and processes for their preparation
摘要 Indolealkylamines of the formula <IMAGE> wherein Ind is 1-R4-2-R5-indol-3-yl or the corresponding group in which the benzene ring is monosubstituted to trisubstituted by alkyl, O-alkyl, S-alkyl, OH, F, Cl, Br, CF3 or CN; A is -(CH2)4-, -(CH2)3-CO- or -CO-(CH2)2-CO-; R1 is H or methyl; R2 is H or together with R3 is a C-C bond; R3 is H or together with R2 is a C-C bond; R4 and R5 are each H, alkyl, or phenyl; and Ar is phenyl or phenyl monosubstituted or disubstituted by alkyl, F, Cl, Br, I or CF3; wherein alkyl in each case is of 1-4 carbon atoms; and the physiologically acceptable acid addition salts thereof possess valuable pharmacological properties.
申请公布号 US4251538(A) 申请公布日期 1981.02.17
申请号 US19790051320 申请日期 1979.06.22
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 HAUSBERG, HANS-HEINRICH;KOPPE, VOLKER;POETSCH, EIKE;SAIKO, OTTO;SEYFRIED, CHRISTOPH
分类号 C07D401/06;(IPC1-7):A61K31/44;C07D209/08 主分类号 C07D401/06
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