发明名称 PROSTACYCLINE DERIVATIVES WITH A CYTOPROTECTIVE ACTION ON THE LIVER, THE PANCREAS AND THE KIDNEY
摘要 <p>Drug for the cytoprotection of the liver, the pancreas and the kidneys, characterized in that it comprises prostacycline derivative having the formula (I) wherein R1 is hydrogen or alkyl with 1 to 10 atoms of carbon, A is group -CH2-CH2-, trans-CH=CH- or -C=C-, W is a hydroxy methyl group, free or functionally transformable on the hydroxy group, wherein the group OH is in position α or β, X is a group CH2 or an oxygen atom, Z is hydrogen or a cyano group, D is a straight or branched chain saturated alkylene group or with 1 to 5 atoms of carbon, E is -C=C- bound or a direct bound, R2 is a straight or branched chain saturated alkyl group with 1 to 7 atoms of carbon, R3 is a free or functionally transformable hydroxy group and, in the case where R1 is hydrogen, their salts with the physiologically acceptable bases.</p>
申请公布号 WO1986000808(A1) 申请公布日期 1986.02.13
申请号 DE1985000245 申请日期 1985.07.18
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