Display of disulfide linked dimeric proteins on filamentous phage

摘要

Methods are provided for the display of a complex homodimer protein on the surface of a bacteriophage particle and combinatorial synthetic libraries of such proteins displayed as a fusion polypeptide with filamentous phage pIX coat protein. Heterodimeric or more complex interchain bonded structure, such as disulfide- linked, multimeric proteins, may be displayed using the method of the invention.