Methods and Systems for Utilizing Sperm for Molecular Delivery

摘要

Disclosed herein include embodiments related to delivery of molecular molecules by a sperm cell to an egg cell for expression, including transient expression, in a fertilized progeny. Further embodiments relate to computerized systems for assisting in the disclosed methods.

主权项

1. A method, comprising:
selecting one or more sperm cells or precursor thereof; transducing the one or more selected sperm cells or precursor thereof with at least one RNA transcript or protein; combining a transduced sperm cell or precursor thereof with an egg cell for fertilization; and receiving molecular information related to the progeny resulting from the fertilization.