发明名称 |
USE OF LIPID CONJUGATES IN THE TREATMENT OF DISEASES |
摘要 |
This invention provides compounds represented by the structure of the general formula (A):;;wherein L is a lipid or a phospholipid, Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol, Y is either nothing or a spacer group ranging in length from 2 to 30 atoms, X is a polymer; and n is a number from 1 to 1000, wherein any bond between L, Z, Y and X is either an amide or an esteric bond. |
申请公布号 |
US2015025233(A1) |
申请公布日期 |
2015.01.22 |
申请号 |
US201414319374 |
申请日期 |
2014.06.30 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY |
发明人 |
YEDGAR Saul |
分类号 |
C08B37/00;A61K31/737;A61K31/728;C08B37/08;A61K47/48 |
主分类号 |
C08B37/00 |
代理机构 |
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代理人 |
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主权项 |
1. A compound represented by the structure of the general formula (A): wherein L is a lipid; Z is either nothing, ethanolamine, serine, phosphate, inositol, choline or glycerol; Y is either nothing or a spacer group ranging in length from 2 to 30 atoms; X is a polymer other than glycosominoglycan; and n is a number from 1 to 1000; wherein said L-Z forms phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, phosphatidylcholine or phosphatidylglycerol. |
地址 |
Jerusalem IL |