发明名称 |
Heterocyclic ring compound having muscle cell or adipocyte differentiation regulating action |
摘要 |
The present invention provides a compound having a muscle cell or adipocyte differentiation regulating action, useful for the prophylaxis or treatment of diseases such as diabetes, obesity, dyslipidemia and the like, and the like, and having superior efficacy.;The present invention provides a compound represented by the formula:;
wherein each symbol is as defined in the description, or a salt thereof. |
申请公布号 |
US8937055(B2) |
申请公布日期 |
2015.01.20 |
申请号 |
US201113810021 |
申请日期 |
2011.07.14 |
申请人 |
Takeda Pharmaceutical Company Limited |
发明人 |
Ujikawa Osamu;Takami Kazuaki;Takakura Nobuyuki;Sakai Nozomu |
分类号 |
A01N57/00;A61K31/675;C07F9/58;A61K31/4418;A61K31/4439;A61K31/506;A61K31/5377;C07D213/56;C07D401/12;C07D413/12 |
主分类号 |
A01N57/00 |
代理机构 |
Wenderoth, Lind & Ponack, L.L.P. |
代理人 |
Wenderoth, Lind & Ponack, L.L.P. |
主权项 |
1. A compound represented by the formula (I): wherein A is an optionally substituted benzene ring, X is CH or N, Y is a bond, —O— or —S—, L1 is a C2-6 alkenylene group, L2 is a C1-6 alkylene group, a C2-6 alkenylene group or a C2-6 alkynylene group, R1 is a hydrogen atom or a C1-6 alkyl group, R2 is (1) a 5- or 6-membered aromatic heterocyclic group optionally substituted by 1 to 3 substituents selected from a halogen atom, a C1-6 alkyl group and a C1-6 alkoxy group, (2) a fused aromatic heterocyclic group of a benzene ring and a 5- or 6-membered heterocycle, wherein the fused aromatic heterocyclic group is optionally substituted by 1 to 3 substituents selected from a halogen atom, a C1-6 alkyl group and a C1-6 alkoxy group, (3) —PO(OR3)2 or (4) —S(O)mR4, R3 is a C1-6 alkyl group, R4 is a C1-6 alkyl group, and m is 0, 1 or 2, or a salt thereof. |
地址 |
Osaka JP |