| 摘要 |
<p>The present invention is directed to a novel method for the preparation of high purity irinotecan hydrochloride. This can be achieved by eliminating the excess of the other reagent, bipi.rho.eridinyl-1' -carbonyl chloride after it has reacted with 7-ethyl-10-hydroxy camptothecin and crystallizing the final product from a suitable solvent.</p> |
