METHOD FOR DETECTING POLYOMAVIRUS REACTIVATION

摘要

The invention provides methods of detection and monitoring of polyomavirus reactivation and active polyomavirus infections using a biological fluid sample. Also provided are methods of risk assessment and risk monitoring of developing a polyomavirus-associated disease.

主权项

1. A method for detection of polyomavirus reactivation in a patient having or suspected of having a latent polyomavirus infection, the method comprising determining the presence or absence of a polyomavirus agnoprotein and/or the presence or absence of agnoprotein antibodies in the biological sample, wherein the biological sample is a body fluid, and wherein the presence of the polyomavirus agnoprotein or agnoprotein antibodies is indicative of reactivation of the polyomavirus in the patient.