Conformable therapeutic shield for vision and pain

摘要

A conformable covering comprises an outer portion with rigidity to resist movement on the cornea and an inner portion to contact the cornea and provide an environment for epithelial regeneration. The inner portion of the covering can be configured in many ways so as to conform at least partially to an ablated stromal surface so as to correct vision. The conformable inner portion may have at least some rigidity so as to smooth the epithelium such that the epithelium regenerates rapidly and is guided with the covering so as to form a smooth layer for vision. The inner portion may comprise an amount of rigidity within a range from about 1×10-4 Pa*m3 to about 5×10-4 Pa*m3 so as to deflect and conform at least partially to the ablated cornea and smooth an inner portion of the ablation with an amount of pressure when deflected.

主权项

1. A method of treating an eye of a patient, the eye comprising a cornea having an ablated stroma, an epithelium and a sclera, the ablated stroma having an ablated profile extending along an optical portion of the cornea, the method comprising:
providing a covering comprising:
an inner portion having an inner rigidity and at least one inner radius of curvature; andan outer portion having an outer rigidity and at least one outer radius of curvature;wherein the inner rigidity is greater than the outer rigidity; and applying the covering against the eye so that the covering flexes with the inner portion at least partially disposed over and substantially conforming to the ablated stroma and with the outer portion engaging the eye along the epithelium, the sclera, or a combination thereof wherein, the engagement holds the inner portion on the optical portion of the cornea; the inner rigidity is from 2.5E-6 Pa-m3 to 6.41E-3 Pa-m3; and the outer rigidity is no more than 4E-5 Pa-m3.