| 发明名称 |
ADJUVANT COMBINATIONS COMPRISING AN NKT ACTIVATOR, A CD40 AGENT, CD40 AGONIST, AND OPTIONAL ANTIGEN, THE USE THROUGH INDUCING SYNERGISTIC CELLULAR IMMUNITY |
| 摘要 |
Adjuvant combinations comprising at least one NKT activator, such as alpha-galactosylceramide (α-Gal-Cer) or iGb3, a CD40 agonist and optionally an antigen are disclosed. The use of these immune adjuvants for treatment of various chronic diseases such as cancers is also provided. |
| 申请公布号 |
US2015004163(A1) |
申请公布日期 |
2015.01.01 |
| 申请号 |
US201414324700 |
申请日期 |
2014.07.07 |
| 申请人 |
IIMMURX, INC. |
发明人 |
AHONEN Cory;NOELLE Randolph |
| 分类号 |
A61K39/39;A61K39/395;A61K45/06;C07K16/46;C07K16/28;A61K31/7032 |
主分类号 |
A61K39/39 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An adjuvant combination which elicits a synergistic effect on T cell immunity comprising:
(i) at least one agonist of CD40; (ii) at least one NKT activator; and (iii) optionally at least one desired antigen. |
| 地址 |
Lebanon NH US |
