Cholecystokinin receptor ligands

摘要

The present invention relates to novel 5-hydroxy-5-aryl-pyrrol-2-ones, their preparation and their use as non-peptide CCK ligands, particularly in pharmaceutical formulations thereof.

主权项

1. A compound of formula (I): wherein X is halogen; Y is hydroxy group or alkoxy group; R is phenyl, cyanophenyl, or halogenated phenyl; R1 is alkyl, branched alkyl, alkenyl, alkynyl, cycloalkyl, alkyloxy, alkylcarbonyl, alkyloxycarbonyl, alkenyl, alkenyloxy, alkenylcarbonyl, phenyl, phenyl alkyl, dialkyl phenyl, benzyl, or benzyl alkyl.