| 发明名称 |
LYSOSOME-CLEAVABLE LINKER |
| 摘要 |
<p>The present invention relates to a linker for forming conjugates of a protein or peptide with a therapeutically active agent and which comprise a thiomaleamic acid moiety that is susceptible to cleavage under the pH conditions prevalent in the lysosome.</p> |
| 申请公布号 |
EP2814512(A1) |
申请公布日期 |
2014.12.24 |
| 申请号 |
EP20130702827 |
申请日期 |
2013.02.05 |
| 申请人 |
UCL BUSINESS PLC. |
发明人 |
SMITH, MARK EDWARD BRENNAN |
| 分类号 |
A61K47/48;A61P35/00 |
主分类号 |
A61K47/48 |
| 代理机构 |
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| 主权项 |
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