| 摘要 |
The present invention relates to a compound of Formula 1, and an SIRT 1 activator including, as an active ingredient, derivatives thereof or pharmaceutically acceptable salts thereof. The present invention also relates to a composition including the SIRT 1 activator for detoxification, for the improvement of metabolic disorders, for the prevention or improvement of eye diseases, or the prevention or improvement of immune diseases. |
| 主权项 |
1. A method for activation sirtuin 1 (SIRT1) in a subject comprising administering an effective amount of a compound of Chemical Formula 1, a derivative thereof or a pharmaceutically acceptable salt thereof to the subject in need thereof: wherein R1, R2, R3 or R4 is independently an unbranched or branched C1-C18 alkyl group, C1-C18 alkoxy group, C1-C18 alkenyl group, C1-C18 alkynyl group or C3-C6 cyclic alkyl group, and R5, R6, R7, R8, R9, R10 or R11 is independently hydrogen or an unbranched or branched C1-C18 alkyl group, C1-C18 alkoxy group, C1-C18 alkenyl group, C1-C18 alkynyl group or C3-C6 cyclic alkyl group. |
