| 主权项 |
1. A method of using a plurality of different types of microarrays to identify and validate biomarkers in a subject, comprising
a. performing one or more assays comprising, in each assay, contacting a target sample comprising a plurality of target biomolecules to a plurality of molecular probes “arrayed” at the distinct known locations on a substrate; b. detecting the reactivity of one or more molecule probes with one or more biomolecules in the target sample in (a); c. performing one or more assays comprising, in each assay, contacting one or more molecular probes to a plurality of target samples, each of which comprising a plurality of target biomolecules, arrayed at the distinct known locations on a substrate; d. detecting the reactivity of the molecular probes with one or more biomolecules in the target samples in (c); e. storing information relating to reactivity between molecular probes and biomolecules in a specimen-linked database of an information management system along with clinical information about target samples; and f. identifying or validating one or more biomarkers using the stored information of the information management system. |
