Methods for identifying fragile histidine triad (FHIT) interaction and uses thereof

摘要

Provided herein are methods and compositions for the diagnosis, prognosis and treatment of a cancer associated disorder using the Fhit gene.

主权项

1. A method for inducing an apoptosis process in a cell, comprising
exposing the cell to an exogenous fragile histidine triad (Fhit) gene product in an amount sufficient to cause generation of reactive oxygen species (ROS) in the cell; and administering an oxidative stress to the cell, wherein the oxidative stress comprises peroxide, thereby inducing an apoptotic process in the cell.