| 摘要 |
The present invention is a portable non-invasive apparatus, system, and method for performing light therapy or photobiomodulation upon the brain tissues through the nostrils of a living mammalian subject for the medical purpose of stimulating the brain in-vivo. In marked difference to conventionally known therapeutic procedures, the present invention utilizes the intranasal pathway as the point of anatomic access; and follows established principles for the conceptual approach that irradiation of the brain tissue with low level light energy of certain fixed parameters would achieve major therapeutic effects in-vivo. In this manner, the present invention utilizes light energy of specified wavelengths, coherency, and pulsed mode to achieve therapeutic outcomes. |
| 主权项 |
1. A self-administrable method for performing non-invasive neurostimulation therapy of the brain via a nasal cavity of a living mammalian on-demand, said self-administrable non-invasive neurostimulation method comprising the steps of:
obtaining a light energy-emitting apparatus comprised of a configured irradiation lens including a portable hollow casing having fixed dimensions, a sized internal spatial volume, and an external surface configuration suitable for in-vivo insertion into the nasal cavity space of a nostril without causing substantial impairment to the subject's ability to breathe and without invading the nasal tissues of the living subject, said portable casing being comprised of (i) a light energy transmitting material which forms at least a portion of the configured external surface for said hollow casing, (ii) at least one light generating unit entirely housed and contained within said internal spatial volume of said hollow casing and which is capable of generating light energy of at least one preselected wavelength selected from the group consisting of near infrared red light wavelengths and visible red light wavelengths, at a predetermined energy intensity and for a preset time duration on-demand sufficient to penetrate through the nasal tissues and to pass into the brain,
whereby said configured irradiation lens can emit light energy in any desired direction within the nasal cavity after in-vivo insertion and achieve passage of said emitted light energy from the nasal cavity into at least one portion of the brain in-vivo; self-administrable applicator means adapted for support of said configured irradiation lens and for at will placement of said light transmitting external surface of said configured irradiation lens at a fixed position and desired irradiation direction within a nostril adjacent to the internal lining of a subject's nasal cavity; a portable controller assembly able to control on-demand delivery of light energy from said configured irradiation lens through the subject's nasal tissues into at least one portion of the brain in-vivo, said controller assembly including (α) a portable and replenishable power source of on-demand direct electrical current, (β) a central processing unit for controlling and directing the flow of such direct electrical current, and (γ) at least one connector in electrical communication with said configured irradiation lens for on-demand conveyance of direct electrical current from said controller assembly to said light generating unit; placing a transparent external surface of said configured irradiation lens within a nostril at a desired fixed position adjacent to the internal lining of a subject's nasal cavity such that light energy emitted by said configured irradiation lens will penetrate through the subject's nasal tissues and pass into at least one portion of the brain in-vivo; and causing said light generating unit of said positioned configured irradiation lens to generate light energy of at least one preselected wavelength selected from the group consisting of near infrared red light wavelengths and visible red light wavelengths, at a predetermined energy intensity and for a preset time duration on-demand sufficient to penetrate through the subject's nasal tissues and to pass into the brain such that neurostimulation of at least one portion of the brain is achieved. |
