| 发明名称 |
Targeted Crosslinked Multilamellar Liposomes |
| 摘要 |
A liposome composition that is useful for treating a subject in need of cancer treatment includes a cross-linked multilamellar liposome having an exterior surface and an interior surface. The interior surface defines a central liposomal cavity. The multilamellar liposome includes at least a first lipid bilayer and a second lipid bilayer. The first lipid bilayer is covalently bonded to the second lipid bilayer. At least one anticancer compound is disposed within the multilamellar liposome. Methods for treating subjects are also provided. |
| 申请公布号 |
US2014356414(A1) |
申请公布日期 |
2014.12.04 |
| 申请号 |
US201414295014 |
申请日期 |
2014.06.03 |
| 申请人 |
University of Southern California |
发明人 |
WANG Pin;WONG Michael KK;GRAY Andrew;JOO Kye-Il;LIU Yarong |
| 分类号 |
A61K9/127;A61K47/48;A61K31/337;A61K45/06;A61K31/713;A61K31/704 |
主分类号 |
A61K9/127 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
a crosslinked multilamellar liposome having an exterior surface and an interior surface, the interior surface defining a central liposomal cavity, the multilamellar liposome including at least a first lipid bilayer and a second lipid bilayer, the first lipid bilayer being covalently bonded to the second lipid bilayer; and at least one anticancer compound within the liposome. |
| 地址 |
Los Angeles CA US |
