PHARMACEUTICAL COMPOSITION COMPRISING N1-CYCLIC AMINE-N5-SUBSTITUTED BIGUANIDE DERIVATIVES AS AN INGREDIENT FOR PREVENTING OR TREATING FIBROSIS
摘要
The present invention provides novel uses of a N1-cyclic amine-N5-substituted biguanide derivative for manufacturing a medicine for preventing or treating fibrosis. The N1-cyclic amine-N5-substituted biguanide derivative effectively inhibits EMT, thereby effectively inhibiting the fibrosis.
申请公布号
KR20140137681(A)
申请公布日期
2014.12.03
申请号
KR20130058493
申请日期
2013.05.23
申请人
HANALL BIOPHARMA CO., LTD.
发明人
KIM, SUNG WUK;LEE, SOON IM;SONG, YEON JUNG;SHIN, MIN JAE;OH, KOOK HWAN;JU, KYUNG DON;SHIN, EUN KYOUNG