| 发明名称 | Gamma-hydroxybutyrate compositions and their use for the treatment of disorders | ||
| 摘要 | Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of making the pharmaceutical compositions and formulations, and methods of their use for the treatment of sleep disorders such as apnea, sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus. | ||
| 申请公布号 | US8901173(B2) | 申请公布日期 | 2014.12.02 |
| 申请号 | US201414172751 | 申请日期 | 2014.02.04 |
| 申请人 | Jazz Pharmacuticals, Inc. | 发明人 | Allphin Clark P.;DesJardin Michael |
| 分类号 | A61K31/19;A61K31/554 | 主分类号 | A61K31/19 |
| 代理机构 | Jones Day | 代理人 | Jones Day |
| 主权项 | 1. A pharmaceutical composition of gamma-hydroxybutyrate (GHB) comprising a mixture of salts of GHB, wherein the mixture comprises three or more salts selected from the group consisting of a sodium salt of gamma-hydroxybutyrate (Na.GHB), a potassium salt of gamma-hydroxybutyrate (K.GHB), a magnesium salt of gamma-hydroxybutyrate (Mg.(GHB)2), and a calcium salt of gamma-hydroxybutyrate (Ca.(GHB)2). | ||
| 地址 | Palo Alto CA US | ||