发明名称 INDAZÓIS 5-HETEROARIL SUBSTITUÍDOS COMO INIBIDORES DE QUINASE
摘要 The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.
申请公布号 BRPI0811065(A2) 申请公布日期 2014.12.02
申请号 BR2008PI11065 申请日期 2008.06.04
申请人 ABBOTT LABORATORIES;ABBOTT GMBH & CO. KG 发明人 IRINI AKRITOPOULOU-ZANZE;BRIAN D. WAKEFIELD;HELMUT MACK;SEAN C. TURNER;ALAN F GASIECKI;VIJAVA J GRACIAS;KATHY SARRIS;DOUGLAS M KALVIN;MELISSA J. MICHMERHUIZEN;QI SHUAI;JYOTI R. PATEL;MARGARETHA BAKKER;NICOLE TEUSCH;ERIC F. JOHNSON;PETER J KOVAR;STEVAN W DJURIC;ANDREW J LONG;ANIL VASUDEVAN;ADRIAN HOBSON;NIGEL ST. JOHN MOORE;LU WANG;DAWN GEORGE;BIQIN LI;KRISTINE FRANK
分类号 C07D403/04;C07D413/04;C07D417/04 主分类号 C07D403/04
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