| 发明名称 | Opioid antagonists | ||
| 摘要 | Certain quinolizidine and octahydropyridopyrazine compounds, pharmaceutical compositions, and methods of their use, inter alia, as opioid receptor antagonists are disclosed. | ||
| 申请公布号 | US8895560(B2) | 申请公布日期 | 2014.11.25 |
| 申请号 | US201414202390 | 申请日期 | 2014.03.10 |
| 申请人 | Adolor Corporation | 发明人 | Dolle Roland E.;Le Bourdonnec Bertrand;Goodman Allan James |
| 分类号 | A61K31/50;A61K31/198;C07D241/36;C07D471/04;A61K31/4985 | 主分类号 | A61K31/50 |
| 代理机构 | Feldman Gale, P.A. | 代理人 | Feldman Gale, P.A. |
| 主权项 | 1. A compound of formula I: wherein: R1 is —C(═O)NH2;X is N—C(═O)-aryl;or a pharmaceutically acceptable salt thereof. | ||
| 地址 | Lexington MA US | ||