| 发明名称 |
MICROORGANISM AND METHOD FOR OVERPRODUCTION OF GAMMA-GLUTAMYLCYSTEINE AND DERIVATIVES OF THIS DIPEPTIDE BY FERMENTATION |
| 摘要 |
The invention relates to a prokaryotic microorganism strain capable of overproducing γ-glutamylcysteine and its derivatives bis-γ-glutamylcystine and γ-glutamylcystine, which can be prepared from a parent strain, wherein said strain has a reduced cellular glutathione synthetase activity compared to the parent strain, and has a cellular γ-glutamylcysteine synthetase activity which is more greatly increased than in a strain with similarly reduced cellular glutathione synthetase activity. |
| 申请公布号 |
US2014342399(A1) |
申请公布日期 |
2014.11.20 |
| 申请号 |
US201414253212 |
申请日期 |
2014.04.15 |
| 申请人 |
Wacker Chemie AG |
发明人 |
THOEN Marcel;SCHLOESSER Thomas |
| 分类号 |
C07K5/062 |
主分类号 |
C07K5/062 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A prokaryotic microorganism strain capable of overproducing γ-glutamylcysteine, bis-γ-glutamylcystine and γ-glutamylcystine, which can be prepared from a parent strain, wherein said prokaryotic microorganism strain has a reduced cellular glutathione synthetase activity compared to the parent strain, and has a cellular γ-glutamylcysteine synthetase activity which is more greatly increased than in a strain with similarly reduced cellular glutathione synthetase activity. |
| 地址 |
Muenchen DE |
