发明名称 PROCESS FOR PREPARING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
摘要 The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith.
申请公布号 US2014336393(A1) 申请公布日期 2014.11.13
申请号 US201414326930 申请日期 2014.07.09
申请人 Vertex Pharmaceuticals Incorporated 发明人 Ambhaikar Narendra Bhalchandra;Hughes Robert;Hurley Dennis James;Lee Elaine Chungmin;Littler Benjamin;Numa Mehdi;Roeper Stefanie;Sheth Urvi
分类号 C07D487/08 主分类号 C07D487/08
代理机构 代理人
主权项
地址 Boston MA US