发明名称 2-ACYL-4-OXY-1,2-DIHYDROPYRROL-5-ONE COMPOUNDS FOR IMPROVING MEMORY AND COGNITIVE FUNCTION
摘要 The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain compounds of the following formula (for convenience, collectively referred to herein as "2-acyl-4-oxy-1,2-dihydropyrrol-5-one compounds" and "DHP compounds"), which, inter alia, are useful in methods of improving memory and/or cognitive function, and in the treatment of memory-related disorders and cognitive decline. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions in the treatment of central nervous system (CNS) disorders such as memory deficit, memory-related disorders, disorders associated with cognitive decline, cognitive impairment, including, for example, mild cognitive impairment (MCI), dementia, and Alzheimer's disease.
申请公布号 WO2014181101(A1) 申请公布日期 2014.11.13
申请号 WO2014GB51391 申请日期 2014.05.07
申请人 UCL BUSINESS PLC 发明人 HILTON, STEPHEN;RUIZ, ARNAUD;SZULC, BLANKA
分类号 C07D207/38;A61K31/4015;A61P25/28 主分类号 C07D207/38
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