发明名称 Method for producing surfactin and salt thereof
摘要 The method for producing a surfactin or a salt thereof according to the present invention comprises the steps of adding an organic solvent containing a branched alkyl alcohol to a culture fluid containing the surfactin or the salt thereof, or to a solution obtained by removing an insoluble component from the culture fluid, and extracting the surfactin or the salt thereof with the organic solvent,;wherein the surfactin or the salt thereof is represented by the formula (1):; wherein * indicates an optically active center; X is an amino acid selected from leucine, isoleucine and valine; R is a C9-13 alkyl group or a C9-13 branched alkyl group; and M is an alkali metal, an alkaline earth metal, an optionally-substituted amine or the like.
申请公布号 US8883968(B2) 申请公布日期 2014.11.11
申请号 US201113876734 申请日期 2011.09.30
申请人 Kaneka Corporation 发明人 Izumida Masashi;Kawasaki Hiroaki;Moroshima Tadashi
分类号 C07K1/14;C07K1/30;C07K7/06;C07K1/36 主分类号 C07K1/14
代理机构 Novak Druce Connolly Bove + Quigg LLP 代理人 Novak Druce Connolly Bove + Quigg LLP
主权项 1. A method for producing a surfactin or a salt thereof, comprising the steps of adding an organic solvent containing a branched alkyl alcohol and an auxiliary solvent to a culture fluid containing the surfactin or the salt thereof, or to a solution obtained by removing an insoluble component from the culture fluid, and extracting the surfactin or the salt thereof with the organic solvent, wherein a total ratio of the branched alkyl alcohol and the auxiliary solvent is not less than 0.6 parts by weight and not more than 1.5 parts by weight relative to 1 part by weight of the culture fluid, and the surfactin or the salt thereof is represented by the formula (1): wherein * indicates an optically active center; X is an amino acid selected from leucine, isoleucine and valine; R is a C9-13 linear alkyl group or a C9-13 branched alkyl group; and M is a hydrogen, an alkali metal, an alkaline earth metal, or an optionally-substituted amine.
地址 Osaka JP
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