DEVICES HAVING A CALIBRATION CONTROL REGION, SYSTEMS AND METHODS FOR IMMUNOHISTOCHEMICAL ANALYSES

摘要

The disclosure relates to devices, systems and methods that address the variability in immunohistochemistry (IHC) tests that can lead to inaccurate diagnosis or misdiagnosis while maintaining important structural information within the specimen. The devices may include a control region having a control unit including a plurality of substantially homogenous samples and a biological sample region.

主权项

1. A device configured for immunohistochemical tests of a biological sample using at least one reporter specific to at least one biomarker, comprising:
a substrate, the substrate including a control region and a biological sample region, the control region including a control unit, the control unit including a plurality of control samples of pseudo-tissue, each control sample including at least one of a first material and a second material, the first material including one or more homogenates that are negative for the at least one biomarker, and the second material including one or more homogenates that are positive for the at least one biomarker.