发明名称 |
SYSTEM OF MAPPING FEMORAL HEAD FOR ACETABULAR PROSTHESIS ALIGNMENT |
摘要 |
This invention relates to a process for the preparation of pyrido[2,1-a]isoquinoline derivatives of the formula wherein R1, R2, R3 and R4 are defined in the specification, comprising the optical resolution of an enamine of the formula wherein R1 is lower alkyl, in the presence of an optical active resolving agent to form an (S)-enamine salt of the formula wherein RCO2− is the conjugate base of the resolving agent. |
申请公布号 |
EP2259751(B1) |
申请公布日期 |
2014.11.05 |
申请号 |
EP20090715869 |
申请日期 |
2009.02.25 |
申请人 |
SMITH & NEPHEW, INC. |
发明人 |
MCMAHON, STEPHEN;ALLEN, CHARLES;KELMAN, DAVID |
分类号 |
A61F2/32;A61B19/00;A61F2/00;A61F2/36 |
主分类号 |
A61F2/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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