发明名称 |
Peptides for Treating Alzheimers's Disease and Related Conditions |
摘要 |
A method of treating loss of memory or motor function due to brain neurodegenerative condition, such as Alzheimer's Disease and others, comprising the steps of:
preparing a composition comprising a D peptide and a pharmaceutically acceptable carrier,
said D peptide further comprises the general structure: A-B-C-D-E-F-G-H
in which:A is Ala, or absent,B is Ser, Thr or absent,C is Ser, Thr or absent,D is Ser, Thr, Asn, Glu, Arg, Ile, Leu,E is Ser, Thr, Asp, Asn,F is Thr, Ser, Asn, Arg, Gln, Lys, Trp,G is Tyr, andH is Thr, Ser, Arg, Gly,and wherein all amino acids are the D stereoisomeric configuration.;The composition is administered to the patient in a therapeutically effective dose and acts to treat the condition in the patient. |
申请公布号 |
US2014322252(A1) |
申请公布日期 |
2014.10.30 |
申请号 |
US201414263560 |
申请日期 |
2014.04.28 |
申请人 |
Ruff Michael |
发明人 |
Ruff Michael |
分类号 |
C07K7/08;C07K7/06 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating brain neurodegenerative condition in a patient comprising the steps of:
preparing a composition comprising a D peptide and a pharmaceutically acceptable carrier,
said D peptide further comprises the general structure: A-B-C-D-E-F-G-H in which:A is Ala, or absent,B is Ser, Thr or absent,C is Ser, Thr or absent,D is Ser, Thr, Asn, Glu, Arg, Ile, Leu,E is Ser, Thr, Asp, Asn,F is Thr, Ser, Asn, Arg, Gln, Lys, Trp,G is Tyr, andH is Thr, Ser, Arg, Gly,and wherein all amino acids are the D stereoisomeric configuration, and administering said composition to the patient in a therapeutically effective dose, wherein said composition acts to treat the brain neurodegenerative condition in the patient. |
地址 |
Potomac MD US |