发明名称 |
19-NOR NEUROACTIVE STEROIDS AND METHODS OF USE THEREOF |
摘要 |
Provided herein are 3,3-disubstituted19-nor-steroidal compounds according to Formula(I): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions,for example, treatment of sleep disorders, mood disorders,schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders,personality disorders,autism spectrum disorders, pain,traumatic brain injury, vascular diseases,substance abuse disorders and/or withdrawal syndromes, tinnitus, status epilepticus. |
申请公布号 |
WO2014169836(A1) |
申请公布日期 |
2014.10.23 |
申请号 |
WO2014CN75600 |
申请日期 |
2014.04.17 |
申请人 |
SAGE THERAPEUTICS, INC.;BOTELLA, GABRIEL MARTINEZ;HARRISON, BOYD L.;ROBICHAUD, ALBERT JEAN;SALITURO, FRANCESCO G.;BERESIS, RICHARD THOMAS |
发明人 |
BOTELLA, GABRIEL MARTINEZ;HARRISON, BOYD L.;ROBICHAUD, ALBERT JEAN;SALITURO, FRANCESCO G.;BERESIS, RICHARD THOMAS |
分类号 |
C07J7/00;A61K31/573;A61K31/58;A61P25/08;A61P25/18;A61P25/28;A61P25/30;C07J43/00 |
主分类号 |
C07J7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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