| 发明名称 | Apparatus for single-molecule detection | ||
| 摘要 | An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further includes a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell. | ||
| 申请公布号 | US8865078(B2) | 申请公布日期 | 2014.10.21 |
| 申请号 | US201012805411 | 申请日期 | 2010.07.29 |
| 申请人 | Industrial Technology Research Institute | 发明人 | Chiou Chung-Fan;Tsai Rung-Ywan;Li Yu-Tang;Shih Chih-Tsung;Li Ming-Chia;Chu Chang-Sheng;Chung Shuang-Chao;Chen Jung-Po;Pu Ying-Chih |
| 分类号 | G01N21/00;G01N21/01;G01N21/64;G01N33/50;G01N33/52;G01N33/487;C40B60/12;B82Y15/00;G01N21/77 | 主分类号 | G01N21/00 |
| 代理机构 | Finnegan, Henderson, Farabow, Garrett & Dunner, LLP | 代理人 | Finnegan, Henderson, Farabow, Garrett & Dunner, LLP |
| 主权项 | 1. A single molecule detection apparatus, comprising: a) a waveguide comprising: a core layer; anda first cladding layer made of a dielectric material, whereinat least one nanowell is formed in at least the first cladding layer, andan upper opening of the at least one nanowell is larger than a bottom of the at least one nanowell; b) a first opaque protection layer arranged over the first cladding layer without extending into the at least one nanowell; c) a second opaque protection layer arranged below the waveguide, the second opaque protection layer having a nanostructured metal pattern; and d) at least one light detector. | ||
| 地址 | Hsinchu TW | ||