发明名称 METHOD FOR PREDICTION OF NON-DEVELOPING PREGNANCY
摘要 FIELD: medicine.SUBSTANCE: invention refers to medicine, namely to obstetrics and gynaecology, and can be used for the prediction of a non-developing pregnancy (NP). Substance of the method: uterine or menstrual aspirate supernatant is examined for carbonyl groups of protein and malondialdehyde at the same time. If the values of the carbonyl groups are 9.43 to 16.91 nmole/ml, and the values of malodialdehyde are 0.71 mcmole/l to 7.28 mcmole/l of malonaldehyde, they are stated to have no negative effect on the endometrium and the gestational sac. If the values of the carbonyl groups fall within the range of 22.32 nmole/mg and more, and if the values of malondialdehyde exceed 7.28 mcmole/l, their negative effect on the gestational sac and a high risk of a non-developing pregnancy are stated. The invention aims at optimising the method for the prediction of a non-developing pregnancy at the pre-clinical stage, at the preventing the negative effect of oxidative stress products on the endometrium at the stage of pre-conceptional preparation.EFFECT: method is characterised by low invasiveness, technical simplicity, accessibility in women's health clinics and hospitals.6 ex
申请公布号 RU2531084(C1) 申请公布日期 2014.10.20
申请号 RU20130133366 申请日期 2013.07.17
申请人 GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "ASTRAKHANSKAJA GOSUDARSTVENNAJA MEDITSINSKAJA AKADEMIJA" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII (GBOU VPO AGMA MINZDRAV A ROSSII) 发明人 TISHKOVA OL'GA GENNAD'EVNA;DIKAREVA LJUDMILA VASIL'EVNA;TEPLYJ DAVID L'VOVICH;TEPLYJ DMITRIJ DAVIDOVICH
分类号 G01N33/50 主分类号 G01N33/50
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