| 发明名称 |
MELATONIN-BASED SOLUTIONS AND POWDERS FOR THEIR PREPARATION |
| 摘要 |
The present invention relates to a powder for reconstitution before use for preparations for injection containing melatonin, at least one soluble excipient and at least one surfactant for the treatment of neonatal cerebral infarction. The present invention also relates to a preparation for injection in the form of a solution obtained by dissolving a powder to be reconstituted comprising melatonin, at least one soluble excipient and at least one surfactant, in a mixture of water and polyalkylene glycol, in which the melatonin is present in quantities of from 3 to 30 mg/ml and the polyalkylene glycol is present in quantities from 5 to 40% of the total volume of the liquid used. |
| 申请公布号 |
US2014308357(A1) |
申请公布日期 |
2014.10.16 |
| 申请号 |
US201214357349 |
申请日期 |
2012.11.09 |
| 申请人 |
Eratech S.R.L. |
发明人 |
Maggi Loretta;Caponetti Giovanni |
| 分类号 |
A61K47/26;A61K9/14;A23C9/20;A61K47/10;A61K47/34;A61K31/4045;A61K47/18 |
主分类号 |
A61K47/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A powder for use as a medicament, wherein it comprises melatonin in an amounts from 35 to 90% in weight, at least one water soluble excipient in an amount from 5 to 60% in weight and at least one water soluble surfactant in an amount from 0.5 to 5% of the total weight of the powder, said powder having an X90 of less than 100 μm and a VDM of less than 50 μm. |
| 地址 |
Milano IT |
