发明名称 INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING LFA-1
摘要 The invention relates to compounds of formula I: wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula I for use in the manufacture and delivery of conjugated moieties such as small molecules, peptides, nucleic acids, fluorescent moieties, and polymers which are linked to LFA-1 integrin antagonists to target cells expressing LFA-1.
申请公布号 KR20140121453(A) 申请公布日期 2014.10.15
申请号 KR20147023815 申请日期 2013.01.24
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GOODNOW JR. ROBERT ALAN;HAMILTON MATTHEW MICHAEL;KOWALCZYK AGNIESZKA;SIDDURI ACHYUTHARAO
分类号 C07D403/12;A61K47/48;A61P29/00;A61P35/00;C07D403/02 主分类号 C07D403/12
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