| 发明名称 |
NON-IONIC, LOW OSMOLAR CONTRAST AGENTS FOR DELIVERY OF ANTISENSE OLIGONUCLEOTIDES AND TREATMENT OF DISEASE |
| 摘要 |
Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein. |
| 申请公布号 |
EP2788087(A1) |
申请公布日期 |
2014.10.15 |
| 申请号 |
EP20120855546 |
申请日期 |
2012.12.06 |
| 申请人 |
THE OHIO STATE INNOVATION FOUNDATION;THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL |
发明人 |
BURGHES, ARTHUR;PORENSKY, PAUL;KASPAR, BRIAN |
| 分类号 |
A61P25/28;A61K47/24;A61K49/04;C12N15/113 |
主分类号 |
A61P25/28 |
| 代理机构 |
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