发明名称 |
SYSTEM FOR DETECTING GENES IN TISSUE SAMPLES |
摘要 |
A computer-based specimen analyzer (10) is configured to detect a level of expression of genes in a cell sample by detecting dots that represent differently stained genes and chromosomes in a cell. The color of the stained genes and the chromosomes is enhanced and filtered to produce a dot mask that defines areas in the image that are genes, chromosomes, or non-genetic material. Metrics are determined for the dots and/or pixels in the image of the cell in areas corresponding to the dots. The metrics are fed to a classifier that separates genes from chromosomes. The results of the classifier are counted to estimate the expression level of genes in the tissue samples. |
申请公布号 |
KR20140120321(A) |
申请公布日期 |
2014.10.13 |
申请号 |
KR20147021628 |
申请日期 |
2013.01.29 |
申请人 |
VENTANA MEDICAL SYSTEMS, INC. |
发明人 |
BAMFORD PASCAL;CHUKKA SRINIVAS;MARTIN JIM F.;SARKAR ANINDYA;SERTEL OLCAY;SUZUE ELLEN;VARANGAONKAR HARSHAL |
分类号 |
G06K9/00;C12Q1/68;G06T7/00;G06T7/40 |
主分类号 |
G06K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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