发明名称 |
LOW ASPECT RATIO STAGED CLOSURE DEVICES AND METHODS FOR FREEZE-DRYING, STORING, RECONSTITUTING AND ADMINISTERING LYOPHILIZED PLASMA |
摘要 |
<p>The inventive device and methods described herein address the introduction of a safe and effective freeze-dried biological product, and particularly a plasma product, to a subject in need thereof. The present invention relates to a multifunctional, staged closure device, which also is described as a lyophilization container for plasma (LCP). The device and methods described herein address how to reproducibly achieve a low moisture and substantially oxygen-free atmosphere within a finally hermetically sealed biocompatible low aspect plastic vessel within a standard shelf-stoppering freeze dryer. The present inventive device and methods provide a freeze-dried plasma product that is fully traceable, preserves the constituent plasma activity, is readily prepared in a sterile fashion, is stable, ensures ease of storage and permits rapid reconstitution and delivery to a patient.</p> |
申请公布号 |
WO2014165222(A1) |
申请公布日期 |
2014.10.09 |
申请号 |
WO2014US24844 |
申请日期 |
2014.03.12 |
申请人 |
LYP SCIENCES, INC. |
发明人 |
MCCARTHY, SIMON;BUCKLEY, LISA;PEPPER, CLINT;WINATA, ERVELYN;STARKMAN, BARRY |
分类号 |
F26B5/06 |
主分类号 |
F26B5/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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